EFFECTS OF LIFELONG ETHANOL CONSUMPTION ON RAT LOCUS COERULEUS
نویسندگان
چکیده
منابع مشابه
Effects of lifelong ethanol consumption on rat locus coeruleus.
The effects of lifelong ethanol consumption and ageing on the morphology of locus coeruleus (LC) were studied in alcohol-preferring AA (Alko Alcohol) rats of both sexes. Ethanol (12% v/v) was the only available liquid for the ethanol-consuming rats from 3 months up to 24 months of age. Young (3-month-old) and old (24-month-old) control groups were included in the measurements. The LC morphometr...
متن کاملEffects of ageing and intermittent ethanol exposure on rat locus coeruleus and ethanol-withdrawal symptoms.
In this study, the effects of ethanol and age on the morphology of the locus coeruleus (LC) and on the severity of ethanol-withdrawal symptoms were studied during a 5-week intermittent ethanol exposure. Young (3-4 months) and old (29-30 months) male Wistar rats were given highly intoxicating doses of ethanol by intragastric intubations for 4 days, followed by a 3-day ethanol-withdrawal period. ...
متن کاملEffects of bilateral lesion of the locus coeruleus on the sleep-wake cycle in the rat
Introduction: Noradrenergic cells in LC participate in the process of cortical activation and behavioral arousal. The evidence suggests that locus ceoruleus (LC) plays an important role in the sleep-wake cycle. The aim of this study was stereological estimation of cavity caused by lesion and assessment of sleep stages after bilateral lesion of the LC. Materials and Methods: Male Wistar rats we...
متن کاملNeuropathology of Aging and Long-term Ethanol Consumption Morphological and Immunohistochemical Studies on Rat Cerebellum, Locus Coeruleus and Frontal Cortex
..........................................................................................................................9 Introduction ..................................................................................................................10 Review of the literature ..............................................................................................12 1 Structural brain al...
متن کاملEthanol reversal of cellular tolerance to morphine in rat locus coeruleus neurons.
Consumption of ethanol is a considerable risk factor for death in heroin overdose. We sought to determine whether a mildly intoxicating concentration of ethanol could alter morphine tolerance at the cellular level. In rat locus coeruleus (LC) neurons, tolerance to morphine was reversed by acute exposure of the brain slice to ethanol (20 mM). Tolerance to the opioid peptide [d-Ala(2),N-MePhe(4),...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Alcohol and Alcoholism
سال: 1997
ISSN: 0735-0414,1464-3502
DOI: 10.1093/oxfordjournals.alcalc.a008281